× Home Simple Search Query Builder Structure Search Browse Similarity with FDA Approved Small Molecule Drugs Similarity with ChEMBL compounds Similarity with ZINC Lead-like compounds Cluster Visualization Submission Useful Resources Contact Us
logo
                  
Record - 1 of 1   [TOP]
Compound IDNVIC0028
Compound Structure
DOWNLOAD:
InhibitorMG132
PubChem ID 462382
Drug Bank ID
ChemSpider ID 406728
SMILESCC(C)CC(C=O)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)OCC1=CC=CC=C1
Molecular Weight475.63 g/mol
Target NiV matrix protein
Assay TypeDose-response assay
Assay DescriptionVirus Titre Reduction assay
Assay Source
Cell TypeHeLa
OutcomeRestriction of Matrix protein to the nucleus
IC50 (in nM)0.47
EC50 (in nM)
H-bond Acceptor8
H-bond Donor3
No. of Rotatable Bond Count18
XLogP6.81
PSA113.60
Reference(s)Https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2978725/
PubMed ID [Source Literature] 21085610
CuratorKanikatuteja@gmail.com