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Compound IDNVIC0028
Compound Structure
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InhibitorMG132
PubChem ID 462382
Drug Bank ID
ChemSpider ID 406728
SMILESCC(C)CC(C=O)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)OCC1=CC=CC=C1
Molecular Weight (in g/mol)475.63
TargetNiV matrix protein
Assay TypeDose-response assay
Assay DescriptionVirus Titre Reduction assay
Assay SourceCalbiochem
Cell TypeHeLa cells
OutcomeReduction in viral titers
IC50 (in nM)0.47
EC50 (in nM)
H-bond Acceptor8
H-bond Donor3
No. of Rotatable Bond Count18
XLogP6.81
PSA113.60
Reference(s)https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2978725/
PubMed ID [Source Literature] 21085610
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