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Compound IDNVIC0067
Compound Structure
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InhibitorBenzamil
PubChem ID 108107
Drug Bank ID
ChemSpider ID 97202
SMILESC1=CC=C(C=C1)CN=C(N)NC(=O)C2=C(N=C(C(=N2)Cl)N)N
Molecular Weight (in g/mol)319.753
TargetInhibitor of sodium/hydrogen transporter
Assay TypeHTS immunolabeling assay
Assay DescriptionNon-linear regression analysis
Assay Source
Cell TypeVero cells
OutcomeSodium channel blockage
IC50 (in nM)65040
EC50 (in nM)
H-bond Acceptor7
H-bond Donor5
No. of Rotatable Bond Count6
XLogP2.35
PSA142.80
Reference(s)https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910441/
PubMed ID [Source Literature] 20668647
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