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Compound IDNVIC0062
Compound Structure
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InhibitorPraziquantel
PubChem ID 4891
Drug Bank ID
ChemSpider ID 4722
SMILESC1CCC(CC1)C(=O)N2CC3C4=CC=CC=C4CCN3C(=O)C2
Molecular Weight (in g/mol)312.413 g/mol
TargetL-type calcium channels antagonist
Assay TypeHTS immunolabeling assay
Assay DescriptionNon-linear regression analysis
Assay Source
Cell TypeVero cells
Outcomecalcium channel blockage
IC50 (in nM)33510
EC50 (in nM)
H-bond Acceptor4
H-bond Donor0
No. of Rotatable Bond Count2
XLogP3.65
PSA40.62
Reference(s)https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910441/
PubMed ID [Source Literature] 20668647
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