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Compound IDNVIC0052
Compound Structure
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InhibitorDantrolene
PubChem ID 6914273
Drug Bank ID
ChemSpider ID 5036403
SMILESC1C(=O)NC(=O)N1N=CC2=CC=C(O2)C3=CC=C(C=C3)[N+](=O)[O-]
Molecular Weight (in g/mol)314.257 g/mol
Targetinhibitor of ryanodine receptor mediated calcium release from the ER
Assay TypeHTS immunolabeling assay
Assay DescriptionNon-linear regression analysis
Assay Source
Cell TypeVero cells
Outcomeinhibition of henipavirus replication
IC50 (in nM)12410
EC50 (in nM)
H-bond Acceptor5
H-bond Donor0
No. of Rotatable Bond Count4
XLogP2.89
PSA106.02
Reference(s)https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910441/
PubMed ID [Source Literature] 20668647
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