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Record - 1 of 3   [TOP]
Compound IDNVIC0032
Compound Structure
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Inhibitor09167(2,2,2-trifluoro-N-[3-(N-naphthylcarbamoyl)(4
PubChem ID 4293368
Drug Bank ID
ChemSpider ID 3499535
SMILESC1CCC2=C(C1)C(=C(S2)NC(=O)C(F)(F)F)C(=O)NC3=CC=CC4=CC=CC=C43
Molecular Weight (in g/mol)418.432
TargetReplication
Assay TypeDose-dependent inhibition of LUC2AM
Assay Description
Assay SourceVitas-M Laboratory
Cell TypeHEK 293T cells
OutcomeAblated NiV-LUC2AM activity
IC50 (in nM)
EC50 (in nM)72.3
H-bond Acceptor8
H-bond Donor2
No. of Rotatable Bond Count6
XLogP6.53
PSA86.44
Reference(s)https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100748/
PubMed ID [Source Literature] 24680955
Curatorkanikatuteja@gmail.com

                  
Record - 2 of 3   [TOP]
Compound IDNVIC0032
Compound Structure
DOWNLOAD:
Inhibitor09167(2,2,2-trifluoro-N-[3-(N-naphthylcarbamoyl)(4
PubChem ID 4293368
Drug Bank ID
ChemSpider ID 3499535
SMILESC1CCC2=C(C1)C(=C(S2)NC(=O)C(F)(F)F)C(=O)NC3=CC=CC4=CC=CC=C43
Molecular Weight (in g/mol)418.432
TargetReplication
Assay TypeDose-dependent inhibition of GFP2AM
Assay Description
Assay SourceVitas-M Laboratory
Cell TypeHEK 293T cells
OutcomeAblated NiV-GFP2AM avtivity
IC50 (in nM)
EC50 (in nM)254
H-bond Acceptor8
H-bond Donor2
No. of Rotatable Bond Count6
XLogP6.53
PSA86.44
Reference(s)https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100748/
PubMed ID [Source Literature] 24680955
Curatorkanikatuteja@gmail.com

                  
Record - 3 of 3   [TOP]
Compound IDNVIC0032
Compound Structure
DOWNLOAD:
Inhibitor09167(2,2,2-trifluoro-N-[3-(N-naphthylcarbamoyl)(4
PubChem ID 4293368
Drug Bank ID
ChemSpider ID 3499535
SMILESC1CCC2=C(C1)C(=C(S2)NC(=O)C(F)(F)F)C(=O)NC3=CC=CC4=CC=CC=C43
Molecular Weight (in g/mol)418.432
TargetReplication
Assay TypeDose-dependent inhibition of NiV-MY-99
Assay Description
Assay SourceVitas-M Laboratory
Cell TypeHEK 293T cells
OutcomeAblated NiV-MY-99 activity
IC50 (in nM)
EC50 (in nM)28.9
H-bond Acceptor8
H-bond Donor2
No. of Rotatable Bond Count6
XLogP6.53
PSA86.44
Reference(s)https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100748/
PubMed ID [Source Literature] 24680955
Curatorkanikatuteja@gmail.com