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Record - 1 of 2   [TOP]
Compound IDNVIC0024
Compound Structure
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InhibitorGliotoxin
PubChem ID 6223
Drug Bank ID
ChemSpider ID 5988
SMILESCN1C(=O)C23CC4=CC=CC(C4N2C(=O)C1(SS3)CO)O
Molecular Weight (in g/mol)326.385
TargetCalcium modulation
Assay TypeHTS immunolabeling assay
Assay DescriptionNon-linear regression analysis
Assay Source
Cell TypeVero cells
OutcomeInhibition of NiV infection.
IC50 (in nM)740
EC50 (in nM)
H-bond Acceptor8
H-bond Donor2
No. of Rotatable Bond Count1
XLogP-2.1
PSA131.68
Reference(s)https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910441/
PubMed ID [Source Literature] 20668647
Curatorkanikatuteja@gmail.com

                  
Record - 2 of 2   [TOP]
Compound IDNVIC0024
Compound Structure
DOWNLOAD:
InhibitorGliotoxin
PubChem ID 6223
Drug Bank ID
ChemSpider ID 5988
SMILESCN1C(=O)C23CC4=CC=CC(C4N2C(=O)C1(SS3)CO)O
Molecular Weight (in g/mol)326.385
TargetCalcium modulation
Assay TypeDose-response assay
Assay DescriptionNon-linear regression analysis
Assay Source
Cell TypeVero cells
OutcomeInhibition of NiV infection.
IC50 (in nM)149
EC50 (in nM)
H-bond Acceptor8
H-bond Donor2
No. of Rotatable Bond Count1
XLogP-2.1
PSA131.68
Reference(s)https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2781006/
PubMed ID [Source Literature] 19889218
Curatorkanikatuteja@gmail.com