× Home Simple Search Query Builder Structure Search Browse Similarity with FDA Approved Small Molecule Drugs Similarity with ChEMBL compounds Similarity with ZINC Lead-like compounds Cluster Visualization Submission Useful Resources NVIK VirtualBox Contact Us
Developed & Hosted by:
CSIR-Institute of Microbial Technology, Sector-39A, Chandigarh, India (160036).
*Best view resolution at 1920x1080 px on 24" screen

logo
☰
                  
Record - 1 of 1   [TOP]
Compound IDNVIC0010.1
Compound Structure
DOWNLOAD:
Inhibitor4-oxo-1,4-Dihydroquinoline-3,5-dicarboxylic Acid
PubChem ID 91619677
Drug Bank ID
ChemSpider ID 62941102
SMILESC1=CC(=C2C(=C1)NC=C(C2=O)C(=O)O)C(=O)O
Molecular Weight (in g/mol)233.179
TargetNiV-F protein
Assay TypeNiV F protein-based fusion assay
Assay DescriptionSize of the syncytia
Assay Source
Cell TypeVero cells
OutcomeInhibit NiV-induced virus-cell and cell-cell fusion
IC50 (in nM)
EC50 (in nM)8000
H-bond Acceptor6
H-bond Donor3
No. of Rotatable Bond Count2
XLogP1.46
PSA103.70
Reference(s)https://pubs.acs.org/doi/full/10.1021/jm900411s
PubMed ID [Source Literature] 19499921
Curatorkanikatuteja@gmail.com