× Home Simple Search Query Builder Structure Search Browse Similarity with FDA Approved Small Molecule Drugs Similarity with ChEMBL compounds Similarity with ZINC Lead-like compounds Cluster Visualization Submission Useful Resources NVIK VirtualBox Contact Us
Developed & Hosted by:
CSIR-Institute of Microbial Technology, Sector-39A, Chandigarh, India (160036).
*Best view resolution at 1920x1080 px on 24" screen

logo
☰
                  
Record - 1 of 7   [TOP]
Compound IDNVIC0003
Compound Structure
DOWNLOAD:
InhibitorR1479
PubChem ID 457388
Drug Bank ID
ChemSpider ID 402579
SMILESC1=CN(C(=O)N=C1N)C2C(C(C(O2)(CO)N=[N+]=[N-])O)O
Molecular Weight (in g/mol)284.232
TargetRNA dependent RNA Polymerase
Assay TypeReporter Virus assay
Assay DescriptionDose-response data fitted to a 4-parameter logistic curve
Assay SourceCarbosynth US LLC, San Diego, CA, USA
Cell TypeNCI-H358 cells
OutcomeInhibition of transcription in NiV-Luc2AM
IC50 (in nM)
EC50 (in nM)1120
H-bond Acceptor7
H-bond Donor4
No. of Rotatable Bond Count3
XLogP-2.1
PSA140.97
Reference(s)https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648002/
PubMed ID [Source Literature] 28629988
Curatoranshu@imtech.res.in

                  
Record - 2 of 7   [TOP]
Compound IDNVIC0003
Compound Structure
DOWNLOAD:
InhibitorR1479
PubChem ID 457388
Drug Bank ID
ChemSpider ID 402579
SMILESC1=CN(C(=O)N=C1N)C2C(C(C(O2)(CO)N=[N+]=[N-])O)O
Molecular Weight (in g/mol)284.232
TargetRNA dependent RNA Polymerase
Assay TypeCytopathic effect assay
Assay DescriptionDose-response data fitted to a 4-parameter logistic curve
Assay SourceCarbosynth US LLC, San Diego, CA, USA
Cell TypeNCI-H358 cells
OutcomeReduction in cell viability
IC50 (in nM)
EC50 (in nM)2630
H-bond Acceptor7
H-bond Donor4
No. of Rotatable Bond Count3
XLogP-2.1
PSA140.97
Reference(s)https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648002/
PubMed ID [Source Literature] 28629988
Curatorkanikatuteja@gmail.com

                  
Record - 3 of 7   [TOP]
Compound IDNVIC0003
Compound Structure
DOWNLOAD:
InhibitorR1479
PubChem ID 457388
Drug Bank ID
ChemSpider ID 402579
SMILESC1=CN(C(=O)N=C1N)C2C(C(C(O2)(CO)N=[N+]=[N-])O)O
Molecular Weight (in g/mol)284.232
TargetRNA dependent RNA Polymerase
Assay TypeCytopathic effect assay
Assay DescriptionDose-response data fitted to a 4-parameter logistic curve
Assay SourceCarbosynth US LLC, San Diego, CA, USA
Cell TypeHeLa
OutcomeReduction in cell viability
IC50 (in nM)
EC50 (in nM)13550
H-bond Acceptor7
H-bond Donor4
No. of Rotatable Bond Count3
XLogP-2.1
PSA140.97
Reference(s)https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648002/
PubMed ID [Source Literature] 28629988
Curatorkanikatuteja@gmail.com

                  
Record - 4 of 7   [TOP]
Compound IDNVIC0003
Compound Structure
DOWNLOAD:
InhibitorR1479
PubChem ID 457388
Drug Bank ID
ChemSpider ID 402579
SMILESC1=CN(C(=O)N=C1N)C2C(C(C(O2)(CO)N=[N+]=[N-])O)O
Molecular Weight (in g/mol)284.232
TargetRNA dependent RNA Polymerase
Assay TypeVirus titer reduction assay
Assay DescriptionVisually inquired for CPE
Assay SourceCarbosynth US LLC, San Diego, CA, USA
Cell TypeNCI-H358 cells
OutcomeReduction in cell viability
IC50 (in nM)
EC50 (in nM)1530
H-bond Acceptor7
H-bond Donor4
No. of Rotatable Bond Count3
XLogP-2.1
PSA140.97
Reference(s)https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648002/
PubMed ID [Source Literature] 28629988
Curatorkanikatuteja@gmail.com

                  
Record - 5 of 7   [TOP]
Compound IDNVIC0003
Compound Structure
DOWNLOAD:
InhibitorR1479
PubChem ID 457388
Drug Bank ID
ChemSpider ID 402579
SMILESC1=CN(C(=O)N=C1N)C2C(C(C(O2)(CO)N=[N+]=[N-])O)O
Molecular Weight (in g/mol)284.232
TargetRNA dependent RNA Polymerase
Assay TypeReporter Virus assay
Assay DescriptionDose-response data fitted to a 4-parameter logistic curve
Assay SourceCarbosynth US LLC, San Diego, CA, USA
Cell TypeHeLa
OutcomeInhibition of transcription in NiV-Luc2AM
IC50 (in nM)
EC50 (in nM)5680
H-bond Acceptor7
H-bond Donor4
No. of Rotatable Bond Count3
XLogP-2.1
PSA140.97
Reference(s)https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648002/
PubMed ID [Source Literature] 28629988
Curatorpriyankapaul008@gmail.com

                  
Record - 6 of 7   [TOP]
Compound IDNVIC0003
Compound Structure
DOWNLOAD:
InhibitorR1479
PubChem ID 457388
Drug Bank ID
ChemSpider ID 402579
SMILESC1=CN(C(=O)N=C1N)C2C(C(C(O2)(CO)N=[N+]=[N-])O)O
Molecular Weight (in g/mol)284.232
TargetRNA dependent RNA Polymerase
Assay TypeReporter Virus assay
Assay DescriptionDose-response data fitted to a 4-parameter logistic curve
Assay SourceCarbosynth US LLC, San Diego, CA, USA
Cell TypeNCI-H358 cells
OutcomeInhibition of transcription in NiV-GFP2AM
IC50 (in nM)
EC50 (in nM)1640
H-bond Acceptor7
H-bond Donor4
No. of Rotatable Bond Count3
XLogP-2.1
PSA140.97
Reference(s)https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648002/
PubMed ID [Source Literature] 28629988
Curatorpriyankapaul008@gmail.com

                  
Record - 7 of 7   [TOP]
Compound IDNVIC0003
Compound Structure
DOWNLOAD:
InhibitorR1479
PubChem ID 457388
Drug Bank ID
ChemSpider ID 402579
SMILESC1=CN(C(=O)N=C1N)C2C(C(C(O2)(CO)N=[N+]=[N-])O)O
Molecular Weight (in g/mol)284.232
TargetRNA dependent RNA Polymerase
Assay TypeVirus titer reduction assay
Assay DescriptionVisually assayed for CPE
Assay SourceCarbosynth US LLC, San Diego, CA, USA
Cell TypeHeLa
OutcomeReplication inhibition in wild type NiV
IC50 (in nM)
EC50 (in nM)4000
H-bond Acceptor7
H-bond Donor4
No. of Rotatable Bond Count3
XLogP-2.1
PSA140.97
Reference(s)https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648002/
PubMed ID [Source Literature] 28629988
Curatorpriyankapaul008@gmail.com