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Record - 1 of 2   [TOP]
Compound IDNVIC0033
Compound Structure
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Inhibitor5705213
PubChem IDNR
Drug Bank ID
ChemSpider ID 721677
TargetCathepsin L
Assay Type
Assay Description
Assay Source
Cell Type293FT cells
OutcomeInhibited the entry of NiV-F0 virus
IC50 (in nM)
EC50 (in nM)254
H-bond Acceptor5
H-bond Donor2
No. of Rotatable Bond Count8
XLogP1.67
PSA116.06
Reference(s)Https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3993759/
PubMed ID [Source Literature] 24501399
CuratorNishisharmacool14@gmail.com

                  
Record - 2 of 2   [TOP]
Compound IDNVIC0034
Compound Structure
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Inhibitor7402683
PubChem ID 7402683
Drug Bank ID
ChemSpider ID 660664
SMILESCCNc1nc(nc(n1)N(CC(=O)OC)C#N)NC(C)(C)C
Molecular Weight307.352
TargetCathepsin L
Assay Type
Assay Description
Assay Source
Cell Type293FT cells
OutcomeInhibited the entry of NiV-F0 virus
IC50 (in nM)
EC50 (in nM)28.9
H-bond Acceptor5
H-bond Donor2
No. of Rotatable Bond Count8
XLogP1.63
PSA116.06
Reference(s)Https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3993759/
PubMed ID [Source Literature] 24501399
CuratorNishisharmacool14@gmail.com