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Compound IDNVIC0075
Compound Structure
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InhibitorRottlerin
PubChem ID   5281847
Drug Bank ID
ChemSpider ID4445144
SMILESCC1=C(C(=C(C(=C1O)C(=O)C)O)CC2=C(C3=C(C(=C2O)C(=O)C=CC4=CC=CC=C4)OC(C=C3)(C)C)O)O
Molecular Weight516.546 g/mol
TargetInhibits PKC mediated pathways
Assay TypeHTS immunolabeling assay
Assay DescriptionNon-linear regression analysis
Assay Source
Cell TypeVero cells
OutcomeModerate inhibition of viral replication
IC50 (in nM)19820
EC50 (in nM)
H-bond Acceptor8
H-bond Donor5
No. of Rotatable Bond Count6
XLogP5.12
PSA144.52
Reference(s)Https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910441/
PubMed ID [Source Literature]20668647
CuratorKanikatuteja@gmail.com