logo
                  
Record - 1 of 1   [TOP]
Compound IDNVIC0052
Compound Structure
DOWNLOAD:
InhibitorDantrolene
PubChem ID   6914273
Drug Bank ID
ChemSpider ID5036403
SMILESC1C(=O)NC(=O)N1N=CC2=CC=C(O2)C3=CC=C(C=C3)[N+](=O)[O-]
Molecular Weight314.257 g/mol
TargetInhibitor of ryanodine receptor mediated calcium release from the ER
Assay TypeHTS immunolabeling assay
Assay DescriptionNon-linear regression analysis
Assay Source
Cell TypeVero cells
OutcomeInhibition of henipavirus replication
IC50 (in nM)12410
EC50 (in nM)
H-bond Acceptor5
H-bond Donor0
No. of Rotatable Bond Count4
XLogP2.89
PSA106.02
Reference(s)Https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910441/
PubMed ID [Source Literature]20668647
CuratorKanikatuteja@gmail.com