logo
                  
Record - 1 of 1   [TOP]
Compound IDNVIC0006
Compound Structure
DOWNLOAD:
InhibitorCHEMBL559961
PubChem ID   44191024
Drug Bank ID
ChemSpider ID24624033
SMILESCCN1C=C(C(=O)C2=CC(=C(C=C21)N3CCC(CC3)C(=O)OCC)F)C(=O)NCC4=C(C=C(C=C4)Cl)Cl
Molecular Weight548.436 g/mol
TargetNiV F protein
Assay TypeNiV F protein-based fusion assay
Assay DescriptionSize of the syncytia (average number of nuclei in syncytia) was determined in the microscope
Assay SourceHttps://pubchem.ncbi.nlm.nih.gov/bioassay/420714#section=Source
Cell TypeVero cells
OutcomeInhibit NiV-induced virus-cell and cell?cell fusion
IC50 (in nM)
EC50 (in nM)3000
H-bond Acceptor10
H-bond Donor1
No. of Rotatable Bond Count9
XLogP5.38
PSA78.95
Reference(s)Https://pubs.acs.org/doi/full/10.1021/jm900411s
PubMed ID [Source Literature]19499921
CuratorAnshu@imtech.res.in