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Record - 1 of 3   [TOP]
Compound IDNVIC0004
Compound Structure
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InhibitorFavipiravir
PubChem ID   492405
Drug Bank ID
ChemSpider ID431002
SMILESC1=C(N=C(C(=O)N1)C(=O)N)F
Molecular Weight157.104 g/mol
TargetRNA dependent RNA Polymerase
Assay TypeVirus yield reduction assay
Assay DescriptionPlaque assay
Assay SourceFavipiravir provided by Toyama Chemical Company Ltd
Cell TypeVero CCL81 cells
OutcomeReduction of viral titres in a dose-dependent manner for NiV-Bangladesh (NiV-B)
IC50 (in nM)
EC50 (in nM)44240
H-bond Acceptor4
H-bond Donor2
No. of Rotatable Bond Count1
XLogP-0.3
PSA89.10
Reference(s)Https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5954062/
PubMed ID [Source Literature]29765101
CuratorAnshu@imtech.res.in

                  
Record - 2 of 3   [TOP]
Compound IDNVIC0004
Compound Structure
DOWNLOAD:
InhibitorFavipiravir
PubChem ID   492405
Drug Bank ID
ChemSpider ID431002
SMILESC1=C(N=C(C(=O)N1)C(=O)N)F
Molecular Weight157.104 g/mol
TargetRNA dependent RNA Polymerase
Assay TypeVirus yield reduction assay
Assay DescriptionPlaque assay
Assay SourceFavipiravir provided by Toyama Chemical Company Ltd
Cell TypeVero CCL81 cells
OutcomeReduction of viral titres in a dose-dependent manner for recombinant NiV expressing Gaussia luciferase and eGFP (rNiV-Gluc-eGFP)
IC50 (in nM)
EC50 (in nM)14820
H-bond Acceptor4
H-bond Donor2
No. of Rotatable Bond Count1
XLogP-0.3
PSA89.10
Reference(s)Https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5954062/
PubMed ID [Source Literature]29765101
CuratorAnshu@imtech.res.in

                  
Record - 3 of 3   [TOP]
Compound IDNVIC0004
Compound Structure
DOWNLOAD:
InhibitorFavipiravir
PubChem ID   492405
Drug Bank ID
ChemSpider ID431002
SMILESC1=C(N=C(C(=O)N1)C(=O)N)F
Molecular Weight157.104 g/mol
TargetRNA dependent RNA Polymerase
Assay TypeVirus yield reduction assay
Assay DescriptionPlaque assay
Assay SourceFavipiravir provided by Toyama Chemical Company Ltd
Cell TypeVero CCL81 cells
OutcomeReduction of viral titres in a dose-dependent manner for NiV-Malaysia (NiV-M)
IC50 (in nM)
EC50 (in nM)14570
H-bond Acceptor4
H-bond Donor2
No. of Rotatable Bond Count1
XLogP-0.3
PSA89.10
Reference(s)Https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5954062/
PubMed ID [Source Literature]29765101
CuratorAnshu@imtech.res.in